{"id":15111590,"date":"2026-05-20T10:30:00","date_gmt":"2026-05-20T14:30:00","guid":{"rendered":"https:\/\/www.inthacity.com\/news\/positive-thinking-could-help-boost-your-immune-system\/"},"modified":"2026-05-20T13:01:40","modified_gmt":"2026-05-20T17:01:40","slug":"positive-thinking-could-help-boost-your-immune-system","status":"publish","type":"post","link":"https:\/\/www.inthacity.com\/news\/positive-thinking-could-help-boost-your-immune-system\/","title":{"rendered":"Positive thinking could help boost your immune system"},"content":{"rendered":"<p>The mind can regulate the immune system. And through directed thinking, people can learn to turn on immune-boosting brain areas, a new study finds.<\/p>\n<p>The idea that the brain can influence the body emerged long ago, says Tor Wager. He\u2019s a neuroscientist at Dartmouth University in Hanover, N.H. But only in the last few years have there been \u201creal breakthroughs in understanding the neuroscience behind this,\u201d he says.<\/p>\n<p>Positive expectations turn on one part of the brain\u2019s reward system. This region triggers the feelings of pleasure we get from eating good food, winning a game or receiving a compliment. Nerve cells in this part of the brain respond to such rewards by releasing the chemical <a href=\"https:\/\/www.snexplores.org\/article\/scientists-say-dopamine-definition-pronunciation\">dopamine<\/a>.&nbsp;<\/p>\n<p>Tamar Koren is a physician scientist at Tel Aviv Medical Center in Israel. She was part of a team that used genetic methods to stimulate these \u201creward\u201d cells in mice.<\/p>\n<p>Turning on those neurons brought surprising health benefits. The mice were better able to <a href=\"https:\/\/www.nature.com\/articles\/nm.4133\" rel=\"noopener\">fight bacterial infections<\/a> and <a href=\"https:\/\/www.nature.com\/articles\/s44161-024-00491-3\" rel=\"noopener\">recovered more quickly from heart attacks<\/a>. Stimulating the animals\u2019 reward circuit even <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6045610\/\" rel=\"noopener\">slowed the growth of tumors<\/a>.<\/p>\n<p>The approach looked so promising that Koren\u2019s team wanted to know if it could work for people, too. But the genetic and molecular tools used in mice can\u2019t ethically be used in humans. Instead, the team trained people to turn on their reward circuits with their own thoughts.<\/p>\n<p>Her team shared details on how they did that in the January 19 <em>Nature Medicine<\/em>.<\/p>\n<h2 class=\"wp-block-heading\">Responding to cues<\/h2>\n<p>This line of research grew out of work done in the late 1890s by Ivan Pavlov. This Russian scientist studied how our bodies extract energy and nutrients from food. In one famous experiment, he rang a bell every time he got ready to feed a hungry dog. Before long, just the sound of the bell would make the dog start salivating \u2014 even when there was no food. Psychologists call this a conditioned response. (For this and related work, Pavlov <a href=\"https:\/\/www.nobelprize.org\/prizes\/medicine\/1904\/pavlov\/facts\/\" rel=\"noopener\">would take home the 1904 Nobel Prize<\/a> in physiology or medicine.)<\/p>\n<aside class=\"wp-block-sciencenews-inline-related-post alignleft\">\n<h4><a href=\"https:\/\/www.snexplores.org\/article\/explainer-the-bodys-immune-system\">Explainer: The body\u2019s immune system<\/a><\/h4>\n<\/aside>\n<p>Decades later, Robert Ader and Nicholas Cohen at the University of Rochester\u2019s medical school did something similar in rodents. They gave the animals a cue \u2014 here, a sweet drink \u2014 at the same time they injected a drug that suppresses the immune system. Eventually, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1162023\/\" rel=\"noopener\">giving rats just the drink could trigger the immune change<\/a>.<\/p>\n<p>Such an effect is known as psychosomatic (SY-koh-soh-MAT-ik). It means that the brain can trigger changes in the body after some conditioned cue (such as hearing a dinner bell or getting a sweet drink).<\/p>\n<p>That term can carry stigma. It\u2019s often used to describe real health symptoms \u2014 such as headaches, pain, nausea or skin changes \u2014 that can be triggered or worsened by mood or stress. People might see these health effects as being imagined or trivial.<\/p>\n<aside class=\"wp-block-sciencenews-inline-related-post alignleft\">\n<h4><a href=\"https:\/\/www.snexplores.org\/article\/discovering-the-power-of-placebos-medicine\">Discovering the power of placebos<\/a><\/h4>\n<\/aside>\n<p>But the opposite also occurs, such as getting relief after taking a sugar pill that looked like an actual drug. This is what\u2019s called <a href=\"https:\/\/www.snexplores.org\/article\/scientists-say-placebo\">the placebo (Pluh-SEE-boh) effect<\/a>. Some people also dismiss this, saying it\u2019s not real medicine.<\/p>\n<p>Yet it can be. In fact, some researchers view placebos as an opportunity.<\/p>\n<p>The placebo effect reflects real physical changes. The effect may result from having positive expectations or a sense of hope. Whatever causes it, says Koren, \u201cmaybe we should understand how it works.\u201d That, she says, might help people respond better to treatments.<\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1030\" height=\"589\" src=\"https:\/\/www.snexplores.org\/wp-content\/uploads\/sites\/3\/2026\/05\/1440_mind_vs_immunity_placebo.jpg\" alt=\"A 3D-rendered illustration of a white pill box labeled 'Placebo' in red lettering, surrounded by red and white capsules on a reflective dark surface.\" class=\"wp-image-236607\" \/><figcaption class=\"wp-element-caption\"><span class=\"caption wp-caption-236607\">Placebos, such as sugar pills, contain no medicine but can lead to health benefits. A new study suggesting a link between positive expectations and immune activity might help explain how the body can produce a placebo effect.<\/span><span class=\"credit wp-credit-236607\">Olemedia\/E+\/Getty Images Plus<\/span><\/figcaption><\/figure>\n<h2 class=\"wp-block-heading\">Turning on the placebo effect<\/h2>\n<p>Her team has now tested that. Working with a psychology lab at Tel Aviv University, they recruited 85 young adults. All were employees who needed a <a href=\"https:\/\/www.snexplores.org\/article\/scientists-say-vaccine\">vaccine<\/a> to work at the medical center. This shot is given to ward off the hepatitis B virus (HBV). Seeing how people responded would offer an easy way to measure immune changes.<\/p>\n<p>For the first phase of the experiment, the recruits had functional <a href=\"https:\/\/www.snexplores.org\/article\/scientists-say-mri\">MRI<\/a> (fMRI) scans. They laid in a machine that scans the brain and shows which parts are active. For each 40-second session, participants were told to put their brain to work. Each could choose how they wanted to do so. For instance, they could watch a red dot on the screen. Or recall a trip. Or think about the future. Or solve a math problem.&nbsp;<\/p>\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\n<div class=\"wp-block-embed__wrapper\">\n<\/div><figcaption class=\"wp-element-caption\">The new study used fMRI to measure what parts of the brain were turned on by some training techniques. Learn what fMRI is \u2014 and how it works \u2014 from this short video.<span class=\"credit\">Neuroscientifically Challenged\/YouTube<\/span><\/figcaption><\/figure>\n<p>Afterward, areas of the brain scan got a rating from 0 to 10. Those scores reflected activity in deep-brain regions of the reward pathway. One key region is known as the VTA, short for ventral tegmental area. This is the same area Koren\u2019s team targeted in mice to trigger health benefits.<\/p>\n<p>Some participants were randomly put into a control group. Their scores came from an unrelated brain region.&nbsp;<\/p>\n<p>When someone got a low score, they were asked to focus their thoughts on something else for the next session. If their score rose, they might repeat or refine that thought-focusing strategy. This trial-and-error process, called fMRI neurofeedback, was carried out in 45 to 60 sessions over several weeks. Through it all, participants had one goal: Get the highest score possible.<\/p>\n<p>\u201cThe important thing for us was not the absolute score but the improvement,\u201d says Nitzan Lubianiker. He led this study back when he was a graduate student on the team. (He now works as a psychology researcher at Yale University in New Haven, Conn.)<\/p>\n<p>Right after their final fMRI session, each recruit got the HBV vaccine. This shot instructs the body to make <a href=\"https:\/\/www.snexplores.org\/article\/what-are-antibodies-explainer\">antibodies<\/a>. Those immune <a href=\"https:\/\/www.snexplores.org\/article\/scientists-say-protein\">proteins<\/a> recognize hepatitis B virus and help protect the liver from becoming infected by it. Blood tests measured virus antibodies before and two weeks after each person got their shot.<\/p>\n<p>People who had been better at increasing brain activity in the VTA showed a larger rise in HBV antibodies after vaccination. That indicates a stronger immune response.<s><\/s><\/p>\n<p>The improvement was just a 7 to 10 percent increase in HBV antibodies. Still, that was impressive, says Jonathan Kipnis. He was not involved in the research. But he knows about such things: His lab studies brain-immune connections at Washington University in St. Louis, Mo.<\/p>\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\n<div class=\"wp-block-embed__wrapper\">\n<\/div><figcaption class=\"wp-element-caption\">In this early video, Asya Rolls, who led the new study, explains her team\u2019s interest in learning how thoughts and emotions can control the body\u2019s immune system \u2014 and how people might learn to harness this process.<span class=\"credit\">Technion Institute of Technology\/YouTube<\/span><\/figcaption><\/figure>\n<h2 class=\"wp-block-heading\">Mind-body connection<\/h2>\n<p>\u201cWe were all surprised that there actually was an effect,\u201d says Koren. The response her team saw in lab mice was less surprising because they directly targeted the nerve cells. But getting people to turn on that region through thoughts alone seemed like \u201cscience fiction,\u201d she now says.<\/p>\n<p>And success here did not depend on someone\u2019s personality. People who said on a questionnaire they\u2019re more optimistic or hopeful did not all get higher VTA scores.<\/p>\n<p>But high scorers did have something in common: They tended to choose mental strategies that involve positive expectations. For some, thoughts centered on friends or family. Others focused on experiences. The details didn\u2019t seem to matter, since participants were not told what to think about. Rather, they adjusted their thoughts based on the neurofeedback scores. That was a \u201ccool finding,\u201d says Lubianiker.<\/p>\n<p>The result \u201cemphasizes how much our mental state is relevant to our well-being and day-to-day physiology,\u201d Koren says. \u201cEven if we\u2019re not aware of it.\u201d<\/p>\n<p class=\"inmi-source\">Source: <a href=\"https:\/\/www.snexplores.org\/article\/positive-thinking-boost-immune-system\" target=\"_blank\" rel=\"noopener nofollow\">Science \u2013 sciencenewsforstudents<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>With real-time feedback, people can learn to turn on a part of the brain that helps rev up the immune system, new data show.<\/p>\n","protected":false},"author":1,"featured_media":15111592,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[218],"tags":[],"class_list":["post-15111590","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science"],"featured_image_urls":{"full":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity.jpg",1440,836,false],"thumbnail":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-300x174.jpg",300,174,true],"medium":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-620x360.jpg",620,360,true],"medium_large":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-768x446.jpg",768,446,true],"large":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-940x546.jpg",940,546,true],"1536x1536":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity.jpg",1440,836,false],"2048x2048":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity.jpg",1440,836,false],"post-thumbnail":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-998x665.jpg",998,665,true],"ignition_item":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-670x446.jpg",670,446,true],"ignition_item_lg":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-1340x836.jpg",1340,836,true],"ignition_article_media":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-510x510.jpg",510,510,true],"ignition_minicart_item":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-160x160.jpg",160,160,true],"profile_24":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-24x24.jpg",24,24,true],"profile_48":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-48x48.jpg",48,48,true],"profile_96":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-96x96.jpg",96,96,true],"profile_150":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-150x150.jpg",150,150,true],"profile_300":["https:\/\/www.inthacity.com\/news\/wp-content\/uploads\/2026\/05\/15111590-1440_mind_vs_immunity-300x300.jpg",300,300,true]},"author_info":{"display_name":"news.iNthacity","author_link":"https:\/\/www.inthacity.com\/news\/author\/atombo\/"},"category_info":"<a 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